Should I Take or Avoid GABA With Divalproex Sodium in 2020?

When you are thinking about taking GABA then you should know the relation between GABA With Divalproex Sodium. We know divalproex sodium ER is an extended-release version of divalproex sodium. Patients typically take the extended-release version once per day. The medication improves manic and mixed episodes of bipolar disorder reduces. The frequency of seizures in epilepsy and prevents migraines from occurring. It does not stop a migraine once it starts, however. GABA With Divalproex Sodium

The amino acid GABA is a neurotransmitter that has calming effects in the brain. It can Increase GABA levels by taking medications such as divalproex sodium ER prevents abnormal activity in the brain. That causes seizures manic episodes of bipolar disorder and migraines. Supplement manufacturers market the amino acid GABA as a natural tranquilizer. But no strong evidence indicates that these over-the-counter supplements actually work for any health condition, according to eMedTV. The common belief among scientists is that taking GABA orally does not result in it reaching the brain, according to the Denver Naturopathic Clinic.

Interactions of GABA With Divalproex

GABA supplements do not seem to interact with any drugs, but research is scant, notes eMedTV. does not list any interaction between divalproex sodium ER and GABA. Divalproex sodium ER does interact with numerous other substances, so talk with your health care provider before combining this medication with any other drugs or nutritional or herbal supplements. Some substances that interact with divalproex sodium ER include cold medicines, pain relievers, antacids, allergy medications, calcium, birth control pills, other epilepsy medications, and sedatives. An interaction may involve reduced beneficial effects or increased side effects of one or both substances.

Side effect of GABA With Divalproex

There are some side effects of GABA. So before taking this you need to think about some important things. You should avoid divalproex sodium if you are allergic to it, or if you have:

  • If you have liver disease;
  • A urea cycle disorder; or
  • If you have a genetic mitochondrial disorder such as Alpers disease.

This sodium can cause liver failure that may be fatal If you have children under the age of two years and in people with liver problems caused by a genetic mitochondrial disorder. Before taking this  consult with your doctor and ask them if you have ever had:

  • A family history of a urea cycle disorder or infant deaths with unknown cause;
  • Liver problems caused by a genetic mitochondrial disorder;
  • Depression, mental illness, or suicidal thoughts or actions;
  • HIV or CMV infection.

Final Words about GABA With Divalproex

Divalproex Sodium was first made in 1881 and came into medical use in 1962. It’s included in the World Health Organization’s List of Essential Medicines, the most effective and safe medicines needed in a health system. It is available as a generic medication. In 2016 it was the 129th most prescribed medication in the United States with more than 5 million prescriptions.

They are useful for the prevention of seizures in those with absence seizures, partial seizures, and generalized seizures. Divalproex Sodium can be given intravenously or by mouth. Long and short-acting formulations of tablets exist.

If GABA supplements work as claimed, taking them along with divalproex sodium ER should increase GABA levels beyond that which the medication accomplishes. This would be considered complementary medicine, in which combining a nutritional supplement or herbal remedy with medication is more beneficial than using one or the other alone. While GABA supplements might not actually increase levels of the neurotransmitter, the supplements are not associated with any side effects and generally are considered safe. Ask your health care provider first.

Hope this article helps you to understand the relation between GABA With Divalproex Sodium. If you have any questions feel free to let us know via the comments section. Thank you for visiting our website. Take care. 

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